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Article

Hip geometry variation is associated with bone mineralization pathway gene variants: The Framingham Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 2010

Cheung Ching-Lung, Livshits Gregory, Zhou Yanhua, Meigs James B, McAteer Jarred B, Florez Jose C, Cupples L Adrienne, Demissie Serkalem, Kiel Douglas P, Karasik David

Abstract excerpt

Mineralization of bone matrix is an important process in bone formation; thus defects in mineralization have been implicated in bone mineral density (BMD) and bone structure alterations. Three central regulators of phosphate balance, ALPL, ANKH, and ENPP1, are central in the matrix mineralization process; therefore, the genes encoding them are considered important candidates genes for BMD and bone geometry. To...

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Share to Alkaline Phosphatase
Share to Bone Density

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcification, Physiologic

Share to Osteoporosis

Share to Phosphate Transport Proteins

Share to Phosphoric Diester Hydrolases

Share to Pyrophosphatases

Source

Open in PubMed Open full text

Identifiers

PMID: 19888898
DOI: 10.1359/jbmr.091102
PMCID: PMC3312740

Genes

ENPP1
ALPL
ANKH
HOXA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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