Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort.

doi:10.1111/j.1464-410X.2012.11648.x

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Article

Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort.

BJU international - 1 Sept 2013

Goh Chee L, Saunders Edward J, Leongamornlert Daniel A, Tymrakiewicz Malgorzata, Thomas Karen, Selvadurai Elizabeth D, Woode-Amissah Ruth, Dadaev Tokhir, Mahmud Nadiya, Castro Elena, Olmos David, Guy Michelle, Govindasami Koveela, O'Brien Lynne T, Hall Amanda L, Wilkinson Rosemary A, Sawyer Emma J, Al Olama Ali Amin, Easton Douglas F, Kote-Jarai Zsofia, Parker Chris C, Eeles Rosalind A

Abstract excerpt

OBJECTIVES: To explore the potential prognostic role of family history (FH) of prostate cancer and prostate cancer risk single nucleotide polymorphisms (SNPs) in patients undergoing active surveillance (AS) for prostate cancer. This is the first study to date, which has investigated the potential prognostic role of SNP profiles in an AS cohort PATIENTS AND METHODS: FH data were collected from patients in the...

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PMID: 23320731
DOI: 10.1111/j.1464-410X.2012.11648.x
PMCID: PMC3633604

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