Article
Single-Nucleotide Polymorphism-Based Genetic Risk Score and Patient Age at Prostate Cancer Diagnosis.
JAMA network open - 2 Dec 2019
Na Rong, Labbate Craig, Yu Hongjie, Shi Zhuqing, Fantus Richard J, Wang Chi-Hsiung, Andriole Gerald L, Isaacs William B, Zheng S Lilly, Helfand Brian T, Xu Jianfeng
Abstract excerpt
Importance: Few studies have evaluated the association between a single-nucleotide polymorphism-based genetic risk score (GRS) and patient age at prostate cancer (PCa) diagnosis. Objectives: To test the association between a GRS and patient age at PCa diagnosis and to compare the performance of a GRS with that of family history (FH) in PCa risk stratification. Design, Setting, and Participants: A cohort study of...
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