Article
Apelin gene polymorphism influences apelin expression and obesity phenotypes in Chinese women.
The American journal of clinical nutrition - 1 Sept 2011
Liao Yi-Chu, Chou Wen-Wen, Li Yi-Ning, Chuang Shih-Chang, Lin Wen-Yi, Lakkakula Bhaskar V K S, Yu Ming-Lung, Juo Suh-Hang Hank
Abstract excerpt
BACKGROUND: Apelin, which is a newly identified adipokine, is related to obesity and insulin resistance. A positive correlation between plasma apelin concentrations and obesity traits was reported. OBJECTIVE: We tested associations between apelin gene (APLN) polymorphisms, BMI, and waist circumference (WC) and compared APLN expression levels in cells of different genotypes. DESIGN: Four tagging single nucleotide...
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