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Article

Postprandial total ghrelin suppression is modulated by melanocortin signaling in humans.

The Journal of clinical endocrinology and metabolism - 1 Feb 2013

van der Klaauw Agatha A, Keogh Julia M, Henning Elana, Blackwood Anthea, Haqq Andrea M, Purnell Jonathan Q, Farooqi I Sadaf

Abstract excerpt

CONTENTS: Ghrelin is implicated in meal initiation because circulating levels increase before and fall after meal consumption. In rodents, ghrelin stimulates food intake via hypothalamic circuits expressing the melanocortin 4 receptor (MC4R). OBJECTIVE: The aim of the study was to investigate the impact of central melanocortinergic tone on ghrelin secretion in humans. DESIGN/SETTING/PATIENTS/MAIN OUTCOME MEASURE:...

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Source

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Identifiers

PMID: 23316086
DOI: 10.1210/jc.2012-2553
PMCID: PMC3565120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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