Article
The Melanocortin System behind the Dysfunctional Eating Behaviors.
Nutrients - 14 Nov 2020
Micioni Di Bonaventura Emanuela, Botticelli Luca, Tomassoni Daniele, Tayebati Seyed Khosrow, Micioni Di Bonaventura Maria Vittoria, Cifani Carlo
Abstract excerpt
The dysfunction of melanocortin signaling has been associated with obesity, given the important role in the regulation of energy homeostasis, food intake, satiety and body weight. In the hypothalamus, the melanocortin-3 receptor (MC3R) and melanocortin-4 receptor (MC4R) contribute to the stability of these processes, but MC3R and MC4R are also localized in the mesolimbic dopamine system, the region that responds...
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