Article
Bcr1 functions downstream of Ssd1 to mediate antimicrobial peptide resistance in Candida albicans.
Eukaryotic cell - 1 Mar 2013
Jung Sook-In, Finkel Jonathan S, Solis Norma V, Chaili Siyang, Mitchell Aaron P, Yeaman Michael R, Filler Scott G
Abstract excerpt
In order to colonize the host and cause disease, Candida albicans must avoid being killed by host defense peptides. Previously, we determined that the regulatory protein Ssd1 governs antimicrobial peptide resistance in C. albicans. Here, we sought to identify additional genes whose products govern susceptibility to antimicrobial peptides. We discovered that a bcr1Δ/Δ mutant, like the ssd1Δ/Δ mutant, had increased...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.