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Article

The NDR Kinase Cbk1 Downregulates the Transcriptional Repressor Nrg1 through the mRNA-Binding Protein Ssd1 in Candida albicans.

Eukaryotic cell - 1 Jul 2015

Lee Hye-Jeong, Kim Jong-Myeong, Kang Woo Kyu, Yang Heebum, Kim Jeong-Yoon

Abstract excerpt

NDR (nuclear Dbf2-related) kinases are essential components for polarized morphogenesis, cytokinesis, cell proliferation, and apoptosis. The NDR kinase Cbk1 is required for the hyphal growth of Candida albicans; however, the molecular functions of Cbk1 in hyphal morphogenesis are largely unknown. Here, we report that Cbk1 downregulates the transcriptional repressor Nrg1 through the mRNA-binding protein Ssd1,...

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Share to Candida albicans
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Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyphae

Share to Morphogenesis

Share to RNA-Binding Proteins

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Source

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Identifiers

PMID: 26002720
DOI: 10.1128/EC.00016-15
PMCID: PMC4486675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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