Article
SSD1 is integral to host defense peptide resistance in Candida albicans.
Eukaryotic cell - 1 Aug 2008
Gank Kimberly D, Yeaman Michael R, Kojima Satoshi, Yount Nannette Y, Park Hyunsook, Edwards John E, Filler Scott G, Fu Yue
Abstract excerpt
Candida albicans is usually a harmless human commensal. Because inflammatory responses are not normally induced by colonization, antimicrobial peptides are likely integral to first-line host defense against invasive candidiasis. Thus, C. albicans must have mechanisms to tolerate or circumvent molecular effectors of innate immunity and thereby colonize human tissues. Prior studies demonstrated that an...
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