Article

A Ssd1 homolog impacts trehalose and chitin biosynthesis and contributes to virulence in <i>Aspergillus fumigatus</i>

2019-03-31

Abstract excerpt

Regulation of fungal cell wall biosynthesis is critical to maintain cell wall integrity in the face of dynamic fungal infection microenvironments. In this study, we observe that a yeast ssd1 homolog, ssdA, in the filamentous fungus Aspergillus fumigatus is involved in trehalose and cell wall homeostasis. An ssdA null mutant strain exhibited an increase in trehalose levels and a reduction in colony growth rate....

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Literature Corpus work: d8a3c568-1237-57c1-932d-b33c7ff3fd84
DOI: 10.1101/594341

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