Article
Rice Defensin OsAFP1 is a New Drug Candidate against Human Pathogenic Fungi.
Scientific reports - 30 Jul 2018
Ochiai Akihito, Ogawa Kodai, Fukuda Minami, Ohori Masahiro, Kanaoka Takumi, Tanaka Takaaki, Taniguchi Masayuki, Sagehashi Yoshiyuki
Abstract excerpt
Fungal infections, such as candidiasis and aspergillosis, are some of the most frequent infections in humans. Although antifungal drugs are available for the treatment of these infections, antifungal agents with new mechanisms of action should be developed because of the increasing incidence of drug-resistant pathogens in recent years. In this study, a basic functional analysis of rice defensin OsAFP1, a novel...
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