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Article

CDKN2A deletion in pediatric versus adult glioblastomas and predictive value of p16 immunohistochemistry

14 Jan 2013

Abstract excerpt

Cell cycle regulator genes are major target of mutation in many human malignancies including glioblastomas (GBMs). CDKN2A is one such tumor suppressor gene which encodes p16INK4a protein and serves as an inhibitor of cell cycle progression. Very few studies are available regarding the association of CDKN2A deletion with p16 protein expression in GBMs. There is limited data on the frequency of CDKN2A deletion in...

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PMID: 23311918
DOI: 10.1111/neup.12014

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CDKN2A deletion in pediatric versus adult glioblastomas and predictive value of p16 immunohistochemistryPMID 23311918Read ↗

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