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Article

Understanding genetic variation - the value of systems biology.

British journal of clinical pharmacology - 1 Apr 2014

Hütt Marc-Thorsten

Abstract excerpt

Pharmacology is currently transformed by the vast amounts of genome-associated information available for system-level interpretation. Here I review the potential of systems biology to facilitate this interpretation, thus paving the way for the emerging field of systems pharmacology. In particular, I will show how gene regulatory and metabolic networks can serve as a framework for interpreting high throughput data...

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Identifiers

PMID: 24725073
DOI: 10.1111/bcp.12266
PMCID: PMC3971976

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