Article
Integrative genomics and drug development.
Pharmacogenomics - 1 Feb 2009
Lum Pek Y, Derry Jonathan M J, Schadt Eric E
Abstract excerpt
The pharmaceutical industry faces unprecedented pressures based largely on the inability to bring sufficient new medicines to market. The high failure rate of drug candidates in clinical development highlights a need for new approaches to the study of disease mechanisms and drug discovery. We advocate an integrated approach based on the study of the entire organism leveraging the power of detailed phenotyping,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.