Article

Gene regulatory network structure informs the distribution of perturbation effects

2024-07-05

Abstract excerpt

Gene regulatory networks (GRNs) govern many core developmental and biological processes underlying human complex traits. Even with broad-scale efforts to characterize the effects of molecular perturbations and interpret gene coexpression, it remains challenging to infer the architecture of gene regulation in a precise and efficient manner. Key properties of GRNs, like hierarchical structure, modular organization,...

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Literature Corpus work: ceb04ed0-5f4c-59d7-b269-5fc57adab397
DOI: 10.1101/2024.07.04.602130

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