Article
P21 gene variation and late-onset Alzheimer's disease in the Italian population.
Dementia and geriatric cognitive disorders - 1 Jan 2013
Scacchi R, Gambina G, Moretto G, Corbo R M
Abstract excerpt
BACKGROUND: Variation at the cyclin-dependent kinase inhibitor gene P21 in a patient sample of the Italian population was investigated in search of genetic factors potentially involved in sporadic late-onset Alzheimer's disease (AD). METHODS: Two single nucleotide polymorphisms (SNPs) were studied in this gene: a C>A transversion at codon 31 (ser>arg) in exon 2 (RS1801270) and a C>T transition occurring 20 bp...
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