Article
DJ-1 is a Parkinson's disease susceptibility gene in southern Italy.
Clinical genetics - 1 Feb 2010
De Marco E V, Annesi G, Tarantino P, Nicoletti G, Civitelli D, Messina D, Annesi F, Arabia G, Salsone M, Condino F, Novellino F, Provenzano G, Rocca F E, Colica C, Morelli M, Scornaienchi V, Greco V, Giofrè L, Quattrone A
Abstract excerpt
Mutations in the gene DJ-1 have been shown to be a rare cause of early-onset Parkinson's disease (EOPD). Since DJ-1 mutations have been found in patients with Parkinson's disease (PD) from southern Italy, we aimed to investigate whether polymorphisms within the DJ-1 gene could represent a risk factor for sporadic PD. First, we genotyped 294 patients with PD and 298 controls coming from southern Italy to assess...
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