Molecular genetics of Alzheimer's disease in Italian families.

doi:10.1016/0197-0186(94)90057-4

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Article

Molecular genetics of Alzheimer's disease in Italian families.

Neurochemistry international - 1 Jul 1994

Sorbi S, Nacmias B, Mortilla M, Forleo P, Piacentini S, Amaducci L

Abstract excerpt

We screened 11 families from different regions of Italy by direct sequencing of exon 17 of the APP gene. Two unrelated families carried the APP717 mutation segregating with the disease. These two families originate from two Italian regions which are considered genetically separate. Published stud...

Topics

Alzheimer Disease
Chromosomes, Human, Pair 14
Exons
Genetic Linkage
Humans
Italy
Mutation
Pedigree

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