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Article

Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease.

Current Alzheimer research - 1 May 2013

Li Lixi, Zhang Sufang, Zhang Xin, Li Ting, Tang Yu, Liu Hui, Yang Wendi, Le Weidong

Abstract excerpt

Autophagy plays an important role in Alzheimer's disease (AD). It has been reported that autophagic flux is altered in patients with AD, and application of the autophagy enhancer rapamycin may alleviate the cognitive impairment and amyloid-β (Aβ) neuropathology in transgenic animal model of AD. Since rapamycin is also an immune suppressor, there is a concern that long-term use of rapamycin may bring severe...

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PMID: 23305067
DOI: 10.2174/1567205011310040008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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