Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epilepsy and autophagy modulators: a therapeutic split

16 May 2025

Abstract excerpt

Epilepsy is a neurological disease characterized by repeated unprovoked seizure. Epilepsy is controlled by anti-epileptic drugs (AEDs); however, one third of epileptic patients have symptoms that are not controlled by AEDs in a condition called refractory epilepsy. Dysregulation of macroautophagy/autophagy is involved in the pathogenesis of epilepsy. Autophagy prevents the development and progression of epilepsy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cannabis and Cannabinoid Research
Share to Genetics and Neurodevelopmental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40375490
DOI: 10.1080/15548627.2025.2506292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epilepsy and autophagy modulators: a therapeutic splitPMID 40375490Read ↗

Autophagy and autophagy signaling in Epilepsy: possible role of autophagy activatorSemantic proximity Read ↗

The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterationsSemantic proximity Read ↗

An evaluation of the links between microRNA, autophagy, and epilepsySemantic proximity Read ↗

Emerging Role of the Autophagy/Lysosomal Degradative Pathway in Neurodevelopmental Disorders With EpilepsySemantic proximity Read ↗

Topical Review: Intractable Seizures in Tuberous Sclerosis Complex: From Molecular Pathogenesis to the Rationale for TreatmentSemantic proximity Read ↗

Rich2 inhibits the NLRP3 inflammasome in epilepsy formation by regulating autophagySemantic proximity Read ↗

Epilepsy in Tuberous Sclerosis: Phenotypes, Mechanisms, and Treatments.Semantic proximity Read ↗

The role of mTOR inhibitors in preventing epileptogenesis in patients with TSC: Current evidence and future perspectivesSemantic proximity Read ↗

NLRP3 inflammasome inhibits mitophagy during the progression of temporal lobe epilepsySemantic proximity Read ↗

GLS2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neuronsSemantic proximity Read ↗

Natural Products in Therapeutic Management of Multineurodegenerative Disorders by Targeting AutophagySemantic proximity Read ↗

Beyond Support Cells: Astrocytic Autophagy as a Central Regulator of CNS Homeostasis and Neurodegenerative DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.