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Article

Doublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Jan 2013

Fu Xiaoqin, Brown Kristy J, Yap Chan Choo, Winckler Bettina, Jaiswal Jyoti K, Liu Judy S

Abstract excerpt

Doublecortin (Dcx) is the causative gene for X-linked lissencephaly, which encodes a microtubule-binding protein. Axon tracts are abnormal in both affected individuals and in animal models. To determine the reason for the axon tract defect, we performed a semiquantitative proteomic analysis of the corpus callosum in mice mutant for Dcx. In axons from mice mutant for Dcx, widespread differences are found in...

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Identifiers

PMID: 23303949
DOI: 10.1523/JNEUROSCI.4603-12.2013
PMCID: PMC3711551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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