Article
Identification of neurabin II as a novel doublecortin interacting protein.
Mechanisms of development - 1 Sept 2003
Tsukada Miki, Prokscha Alexander, Oldekamp Judit, Eichele Gregor
Abstract excerpt
The neuronal migration protein doublecortin (DCX) that associates with microtubules through a tandem DCX repeat, is required for the development of the complex architecture of the human cerebral cortex. Using a yeast two-hybrid screen with Dcx as bait, we have isolated neurabin II/spinophilin, an F-actin binding protein known to play a role in dendritic spine formation. The coiled-coil domain of neurabin II binds...
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