Article
Gram-negative enterobacteria induce tolerogenic maturation in dexamethasone conditioned dendritic cells.
PloS one - 1 Jan 2012
Cabezón Raquel, Ricart Elena, España Carolina, Panés Julián, Benitez-Ribas Daniel
Abstract excerpt
Dendritic cells have been investigated in clinical trials, predominantly with the aim of stimulating immune responses against tumours or infectious diseases. Thus far, however, no clinical studies have taken advantage of their specific immunosuppressive potential. Tolerogenic DCs may represent a new therapeutic strategy for human immune-based diseases, such as Crohn's disease, where the perturbations of the...
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