Article
Therapeutic potential of tolerogenic dendritic cells in IBD: from animal models to clinical application.
Clinical & developmental immunology - 1 Jan 2013
Cabezón Raquel, Benítez-Ribas Daniel
Abstract excerpt
The gut mucosa undergoes continuous antigenic exposure from food antigens, commensal flora derived ligands, and pathogens. This constant stimulation results in controlled inflammatory responses that are effectively suppressed by multiple factors. This tight regulation, necessary to maintain intestinal homeostasis, is affected during inflammatory bowel diseases (IBD) resulting in altered immune responses to...
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