Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DISC1: a key lead in studying cortical development and associated brain disorders.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry - 1 Oct 2013

Narayan Soumya, Nakajima Kazunori, Sawa Akira

Abstract excerpt

For the past decade, DISC1 has been studied as a promising lead to understand the biology underlying major mental illnesses, such as schizophrenia. Consequently, many review articles on DISC1 have been published. In this article, rather than repeating comprehensive overviews of research articles, we will introduce the utility of DISC1 in the study of cortical development in association with a wide range of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Brain Diseases
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DISC1 gene

Share to Genetic Predisposition to Disease

Share to Mental Disorders

Share to Nerve Tissue Proteins

Share to Phosphodiesterase function and regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 23300216
DOI: 10.1177/1073858412470168
PMCID: PMC3954825

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DISC1: a key lead in studying cortical development and associated brain disorders.PMID 23300216Read ↗

Understanding the role of DISC1 in psychiatric disease and during normal development.Semantic proximity Read ↗

Role of DISC1 in neural development and schizophrenia.Semantic proximity Read ↗

Linking neurodevelopmental and synaptic theories of mental illness through DISC1.Semantic proximity Read ↗

How has DISC1 enabled drug discovery?Semantic proximity Read ↗

DISC1 genetics, biology and psychiatric illnessSemantic proximity Read ↗

DISC1 at 10: connecting psychiatric genetics and neuroscience.Semantic proximity Read ↗

Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoidsSemantic proximity Read ↗

Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell FateSemantic proximity Read ↗

Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical DevelopmentSemantic proximity Read ↗

Schizophrenia in translation: disrupted in schizophrenia (DISC1): integrating clinical and basic findings.Semantic proximity Read ↗

Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia.Semantic proximity Read ↗

Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1–ErbB4 and DISC1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.