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Article

Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1.

Haematologica - 1 Mar 2013

Ambaglio Ilaria, Malcovati Luca, Papaemmanuil Elli, Laarakkers Coby M, Della Porta Matteo G, Gallì Anna, Da Vià Matteo C, Bono Elisa, Ubezio Marta, Travaglino Erica, Albertini Riccardo, Campbell Peter J, Swinkels Dorine W, Cazzola Mario

Abstract excerpt

Somatic mutations of the RNA splicing machinery have been recently identified in myelodysplastic syndromes. In particular, a strong association has been found between SF3B1 mutation and refractory anemia with ring sideroblasts, a condition characterized by ineffective erythropoiesis and parenchymal iron overload. We studied the relationship between SF3B1 mutation, erythroid activity and hepcidin levels in...

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Identifiers

PMID: 23300182
DOI: 10.3324/haematol.2012.077446
PMCID: PMC3659929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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