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Article

Significance of SF3B1 Mutations in Myeloid Neoplasms.

Clinics in laboratory medicine - 1 Dec 2023

Gajzer David C, Yeung Cecilia C S

Abstract excerpt

Myelodysplastic neoplasm with low blasts and SF3B1 mutation (MDS-LB-SF3B1) has undergone significant classification changes in the past year with the publication of the 5th edition of the World Health Organization Classification of Tumors of Haematopoietic and Lymphoid Tissues and the International Consensus Classification. This article reviews the basic biology of SF3B1, iron metabolism, and dysfunction that...

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PMID: 37865505
DOI: 10.1016/j.cll.2023.07.005

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