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Article

Hippo activation through homodimerization and membrane association for growth inhibition and organ size control.

Developmental biology - 15 Mar 2013

Deng Yaoting, Matsui Yurika, Zhang Yifan, Lai Zhi-Chun

Abstract excerpt

Hippo (Hpo) signaling plays a critical role in restricting tissue growth and organ size in both invertebrate and vertebrate animals. However, how the Hpo kinase is regulated during development has not been clearly understood. Using a Bimolecular Fluorescence Complementation assay, we have investigated the functional significance of Hpo homo-dimer formation and subcellular localization in living cells. We found...

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Identifiers

PMID: 23298890
DOI: 10.1016/j.ydbio.2012.12.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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