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Article

Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila.

Developmental biology - 1 Sept 2012

Ye Xin, Deng Yaoting, Lai Zhi-Chun

Abstract excerpt

Tissue growth is achieved through coordinated cellular growth, cell division and apoptosis. Hippo signaling is critical for monitoring tissue growth during animal development. Loss of Hippo signaling leads to tissue overgrowth due to continuous cell proliferation and block of apoptosis. As cells lacking Hippo signaling are similar in size compared to normal cells, cellular growth must be properly maintained in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22732571
DOI: 10.1016/j.ydbio.2012.06.014

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Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila.PMID 22732571Read ↗

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Hippo signaling pathway and organ size control.Semantic proximity Read ↗

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