Article
The impact of glucocorticoid polymorphisms on markers of neonatal respiratory disease after antenatal betamethasone administration.
American journal of obstetrics and gynecology - 1 Mar 2013
Haas David M, Dantzer Jessica, Lehmann Amalia S, Philips Santosh, Skaar Todd C, McCormick Catherine L, Hebbring Scott J, Jung Jeesun, Li Lang
Abstract excerpt
OBJECTIVE: We previously demonstrated that maternal and fetal genotypes are associated independently with neonatal respiratory distress syndrome. The objective of the current study was to determine the impact of maternal and fetal single-nucleotide polymorphisms (SNPs) in key betamethasone pathways on respiratory outcomes that serve as markers for severity of disease. STUDY DESIGN: DNA was obtained from women who...
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