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Article

Systemic Steroid Exposure Is Associated with Differential Methylation in Chronic Obstructive Pulmonary Disease

1 Dec 2012

Abstract excerpt

RATIONALE: Systemic glucocorticoids are used therapeutically to treat a variety of medical conditions. Epigenetic processes such as DNA methylation may reflect exposure to glucocorticoids and may be involved in mediating the responses and side effects associated with these medications. OBJECTIVES: To test the hypothesis that differences in DNA methylation are associated with current systemic steroid use. METHODS:...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 23065012
DOI: 10.1164/rccm.201207-1280oc

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