Article
Steroid Pathway Genes and Neonatal Respiratory Distress After Betamethasone Use in Anticipated Preterm Birth.
Reproductive sciences (Thousand Oaks, Calif.) - 1 May 2016
Haas David M, Lai Dongbing, Sharma Sunita, Then Jenny, Kho Alvin, Flockhart David A, Tantisira Kelan, Foroud Tatiana
Abstract excerpt
OBJECTIVE: To test several key glucocorticoid genes that are enhanced in lung development for associations with respiratory distress syndrome (RDS) after antenatal corticosteroid use. METHODS: A prospective cohort of women received betamethasone to accelerate fetal lung maturity for threatened preterm delivery. DNA was obtained from mothers and newborns. Neonatal RDS was the primary outcome. Genotyping for...
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