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Article

Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma.

Respiratory research - 20 Jul 2009

Raby Benjamin A, Van Steen Kristel, Lasky-Su Jessica, Tantisira Kelan, Kaplan Feige, Weiss Scott T

Abstract excerpt

BACKGROUND: Glucocorticoid function is dependent on efficient translocation of the glucocorticoid receptor (GR) from the cytoplasm to the nucleus of cells. Importin-13 (IPO13) is a nuclear transport receptor that mediates nuclear entry of GR. In airway epithelial cells, inhibition of IPO13 expres...

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Source

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Identifiers

PMID: 19619331
DOI: 10.1186/1465-9921-10-67
PMCID: PMC2724419

Genes

IPO13
AHR
CAMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19619331-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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