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Article

Deconvolving the roles of Wnt ligands and receptors in sensing and amplification.

Molecular systems biology - 1 Jan 2013

Tan Rui Zhen, Ji Ni, Mentink Remco A, Korswagen Hendrik C, van Oudenaarden Alexander

Abstract excerpt

Establishment of cell polarity is crucial for many biological processes including cell migration and asymmetric cell division. The establishment of cell polarity consists of two sequential processes: an external gradient is first sensed and then the resulting signal is amplified and maintained by intracellular signaling networks usually using positive feedback regulation. Generally, these two processes are...

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Identifiers

PMID: 23295860
DOI: 10.1038/msb.2012.64
PMCID: PMC3564265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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