Modeling polarity buildup and cell fate decision in the fly eye: insight into the connection between the PCP and Notch pathways.

Abstract excerpt

Metazoan development critically depends on a surprisingly short list of conserved pathways. How can such ubiquitous systems regulate a variety of cell-biological events at various developmental stages in different tissues and in different organisms? In the fruit fly, the planar cell polarity (PCP) pathway regulates widely different processes. It is known to be involved in the correct alignment of hairs on the...

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