Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between the lymphotoxin-alpha gene polymorphism and chagasic cardiopathy.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Mar 2013

Pissetti Cristina Wide, de Oliveira Rafael Faria, Correia Dalmo, Nascentes Gabriel Antonio Nogueira, Llaguno Mauricio Manoel, Rodrigues Virmondes

Abstract excerpt

Lymphotoxin-alpha (LT-alpha or LTA) is an inflammatory cytokine that is involved in the organization and maintenance of the inflammatory process and in the arrangement of cells at the site of inflammation. These features suggest an important role in the development of chronic Chagas' disease, especially the cardiac form. The objective of this study was to evaluate LT-alpha genetics and its biological role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Antigens, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Chagas Cardiomyopathy

Share to Gene Expression Regulation

Share to Lymphotoxin-alpha

Share to Polymorphism, Restriction Fragment Length

Share to Trypanosoma cruzi

Source

Identifiers

PMID: 23289732
DOI: 10.1089/jir.2012.0024

Genes

LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between the lymphotoxin-alpha gene polymorphism and chagasic cardiopathy.PMID 23289732Read ↗

Polymorphisms in the gene for lymphotoxin-alpha predispose to chronic Chagas cardiomyopathy.Semantic proximity Read ↗

Genetic susceptibility to chronic Chagas disease: an overview of single nucleotide polymorphisms of cytokine genes.Semantic proximity Read ↗

Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese.Semantic proximity Read ↗

Single nucleotide polymorphisms of cytokine-related genes and association with clinical outcome in a Chagas disease case-control study from Brazil.Semantic proximity Read ↗

Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.Semantic proximity Read ↗

An association study in essential hypertension using functional polymorphisms in lymphotoxin-alpha gene.Semantic proximity Read ↗

Association of lymphotoxin-alpha gene polymorphisms (rs909253, rs1800683 and rs2229094) and risk of large-artery atherosclerosis stroke in Iranian population.Semantic proximity Read ↗

Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.Semantic proximity Read ↗

Assessment of Galectin-3 Polymorphism in Subjects with Chronic Chagas Disease.Semantic proximity Read ↗

Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease.Semantic proximity Read ↗

Chagas Disease Cardiomyopathy: Immunopathology and GeneticsSemantic proximity Read ↗

The genetic association between polymorphisms in lymphotoxin-α gene and ankylosing spondylitis susceptibility in Chinese group: A case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.