Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese.

doi:10.1620/tjem.224.119

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Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese.

The Tohoku journal of experimental medicine - 1 Jun 2011

Liu Yan, Sheng Haihui, Lu Lin, Wu Zhijun, Chen Qiujin, Xiao Huasheng, Jin Wei

Abstract excerpt

Lymphotoxin-alpha (LTA), a pro-inflammatory cytokine, has been implicated in the pathogenesis of coronary atherosclerosis. Meanwhile, association of some single nucleotide polymorphisms (SNPs) of LTA gene with coronary artery disease (CAD) has been evaluated; however, the results are irreproducible. We therefore investigated the relationship between four SNPs of LTA gene and CAD in Han Chinese: G+10A (rs1800683,...

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PMID: 21628868
DOI: 10.1620/tjem.224.119

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