Article
An association study in essential hypertension using functional polymorphisms in lymphotoxin-alpha gene.
American journal of hypertension - 1 Nov 2004
Nakayama Tomohiro, Soma Masayoshi, Sato Naoyuki, Haketa Akira, Kosuge Kotoko, Aoi Noriko, Sato Mikano, Izumi Yoichi, Matsumoto Koichi, Kanmatsuse Katsuo, Kokubun Shinichiro
Abstract excerpt
BACKGROUND: Lymphotoxin-alpha (LTA), a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The substance LTA mediates a wide variety of inflammatory, immunostimulatory, and antiviral responses. In 2002, LTA was identified as a major risk factor for myocardial infarction (MI) in Japanese individuals, in a large-scale case-control study using 92,788 gene-based single-nucleotide...
Topics
Join the communities discussing this publication.