Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease.

Clinical science (London, England : 1979) - 1 Mar 2007

Asselbergs Folkert W, Pai Jennifer K, Rexrode Kathryn M, Hunter David J, Rimm Eric B

Abstract excerpt

The pro-inflammatory cytokine LTA (lymphotoxin-alpha) has multiple functions in regulating the immune system and may contribute to inflammatory processes leading to CHD (coronary heart disease). The aim of the present study was to investigate whether the common C804A (resulting in a Thr(26)-->Asp amino acid substitution) and A252G polymorphisms of the LTA gene and the C3279T polymorphism of the galectin-2...

Topics

Join the communities discussing this publication.

Age Factors
Biomarkers
Cell Adhesion Molecules
Coronary Disease
Epidemiologic Methods

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Inflammation Mediators

Lymphotoxin-alpha

Myocardial Infarction

Source

Identifiers

PMID: 17040205
DOI: 10.1042/CS20060200

Genes

LTA
LGALS2
CRP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease.PMID 17040205Read ↗

Lack of association between lymphotoxin-alpha, galectin-2 polymorphisms and coronary artery disease: a meta-analysis.Semantic proximity Read ↗

Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.Semantic proximity Read ↗

Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.Semantic proximity Read ↗

Genome-wide association study to identify SNPs conferring risk of myocardial infarction and their functional analyses.Semantic proximity Read ↗

Inflammation as a risk factor for myocardial infarction.Semantic proximity Read ↗

Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese.Semantic proximity Read ↗

Galectin-2 3279TT variant protects against the lymphotoxin-alpha 252GG genotype associated ischaemic stroke.Semantic proximity Read ↗

Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.Semantic proximity Read ↗

Lymphotoxin 252A>G polymorphism is common and associates with myocardial infarction in patients with rheumatoid arthritis.Semantic proximity Read ↗

Association between the lymphotoxin-alpha gene polymorphism and chagasic cardiopathy.Semantic proximity Read ↗

Association of lymphotoxin-alpha gene polymorphisms (rs909253, rs1800683 and rs2229094) and risk of large-artery atherosclerosis stroke in Iranian population.Semantic proximity Read ↗

Four genetic polymorphisms of lymphotoxin-alpha gene and cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.