Article
Assessment of Galectin-3 Polymorphism in Subjects with Chronic Chagas Disease.
Arquivos brasileiros de cardiologia - 1 Nov 2015
Cruz Gabriela da Silva, Angelo Ana Luiza Dias, Larocca Ticiana Ferreira, Macedo Carolina Thé, Noya-Rabelo Márcia, Correia Luís Claudio Lemos, Torreão Jorge Andion, Souza Bruno Solano de Freitas, Santos Ricardo Ribeiro Dos, Soares Milena Botelho Pereira
Abstract excerpt
BACKGROUND: Galectin-3, a β-galactoside binding lectin, has been described as a mediator of cardiac fibrosis in experimental studies and as a risk factor associated with cardiovascular events in subjects with heart failure. Previous studies have evaluated the genetic susceptibility to Chagas disease in humans, including the polymorphisms of cytokine genes, demonstrating correlations between the genetic...
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