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[Effect of overexpression of nicotinic acid mononucleotide adenylyltransferase on succinic acid production in Escherichia coli NZN111].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Sept 2012

Gou Dongmei, Liang Liya, Liu Rongming, Zhang Changqing, Wu Mingke, Ma Jiangfeng, Chen Kequan, Zhu Jianguo, Jiang Min

Abstract excerpt

Escherichia coli NZN111 is a promising strain with ldhA and pflB genes inactivated for the production of succinic acid. However, with these mutations, NAD+ could not be regenerated from NADH, and an unbalanced NADH/NAD+ ratio eliminated cell growth and glucose utilization under anaerobic conditions. Nicotinic acid mononucleotide adenylyltransferase (NAMNAT), encoded by the nadD gene, catalyzes the reaction from...

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PMID: 23289308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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