Article
Technical brief: isolation of total DNA from postmortem human eye tissues and quality comparison between iris and retina.
Molecular vision - 1 Jan 2012
Wang Jay Ching Chieh, Wang Aikun, Gao Jiangyuan, Cao Sijia, Samad Idris, Zhang Dean, Ritland Carol, Cui Jing Z, Matsubara Joanne Aiko
Abstract excerpt
BACKGROUND: Recent genomic technologies have propelled our understanding of the mechanisms underlying complex eye diseases such as age-related macular degeneration (AMD). Genotyping postmortem eye tissues for known single nucleotide polymorphisms (SNPs) associated with AMD may prove valuable, especially when combined with information obtained through other methods such as immunohistochemistry, western blot,...
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