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Article

Characterization of retinal and blood mitochondrial DNA from age-related macular degeneration patients.

Investigative ophthalmology & visual science - 1 Aug 2010

Kenney M Cristina, Atilano Shari R, Boyer David, Chwa Marilyn, Chak Garrick, Chinichian Sahmon, Coskun Pinar, Wallace Douglas C, Nesburn Anthony B, Udar Nitin S

Abstract excerpt

PURPOSE: To determine mitochondrial (mt)DNA variants in AMD and age-matched normal retinas. METHODS: Total DNA was isolated from retinas (AMD, n = 13; age-matched normal, n = 13), choroid (AMD, n = 3), and blood (AMD, n = 138; normal, n = 133). Long-extension-polymerase chain reaction amplified the full-length ( approximately 16.2 kb) mtDNA genome. Retinal mtDNA was sequenced for nucleotide variants and length...

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Share to Macular Degeneration
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Gene Rearrangement

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 20357205
DOI: 10.1167/iovs.09-4778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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