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Article

Mitochondrial DNA haplogroups associated with age-related macular degeneration.

Investigative ophthalmology & visual science - 1 Jun 2009

Udar Nitin, Atilano Shari R, Memarzadeh Masood, Boyer David S, Chwa Marilyn, Lu Stephanie, Maguen Barak, Langberg Jonathan, Coskun Pinar, Wallace Douglas C, Nesburn Anthony B, Khatibi Nikan, Hertzog Dieter, Le Khoi, Hwang Daniel, Kenney M Cristina

Abstract excerpt

PURPOSE: To examine the mtDNA control regions in normal and age-related macular degeneration (AMD) retinas. To identify the mtDNA variations associated with AMD. METHODS: Retinas from 10 normal and 11 AMD globes were isolated and analyzed for mtDNA rearrangements by long extension-polymerase chain reaction (LX-PCR) and for the nature and frequency of single-nucleotide polymorphisms (SNPs) in the mtDNA control...

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Share to Aged, 80 and over
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Macular Degeneration

Share to Oxidative Stress

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 19151382
DOI: 10.1167/iovs.08-2646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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