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Article

Investigating Mitochondria as a Target for Treating Age-Related Macular Degeneration

6 May 2015

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of blindness among older adults in the developed world. Although the pathological mechanisms have not been definitively elucidated, evidence suggests a key role for mitochondrial (mt) dysfunction. The current study used our unique collection of human retinal samples graded for the donor's stage of AMD to address fundamental questions about mtDNA damage...

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PMID: 25948278
DOI: 10.1523/jneurosci.0190-15.2015

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