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Article

Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases.

Proceedings of the National Academy of Sciences of the United States of America - 29 Jun 2010

Osakabe Keishi, Osakabe Yuriko, Toki Seiichi

Abstract excerpt

Site-directed mutagenesis in higher plants remains a significant technical challenge for basic research and molecular breeding. Here, we demonstrate targeted-gene inactivation for an endogenous gene in Arabidopsis using zinc finger nucleases (ZFNs). Engineered ZFNs for a stress-response regulator...

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Identifiers

PMID: 20508151
DOI: 10.1073/pnas.1000234107
PMCID: PMC2900650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20508151-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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