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Article

Detailed analysis of targeted gene mutations caused by the Platinum-Fungal TALENs in Aspergillus oryzae RIB40 strain and a ligD disruptant.

Journal of bioscience and bioengineering - 1 Mar 2017

Mizutani Osamu, Arazoe Takayuki, Toshida Kenji, Hayashi Risa, Ohsato Shuichi, Sakuma Tetsushi, Yamamoto Takashi, Kuwata Shigeru, Yamada Osamu

Abstract excerpt

Transcription activator-like effector nucleases (TALENs), which can generate DNA double-strand breaks at specific sites in the desired genome locus, have been used in many organisms as a tool for genome editing. In Aspergilli, including Aspergillus oryzae, however, the use of TALENs has not been validated. In this study, we performed genome editing of A. oryzae wild-type strain via error of nonhomologous...

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PMID: 27780671
DOI: 10.1016/j.jbiosc.2016.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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