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Interethnic differences in UGT1A4 genetic polymorphisms between Mexican Mestizo and Spanish populations.

Molecular biology reports - 1 Apr 2013

López Marisol, Dorado Pedro, Ortega Alberto, Peñas-Lledó Eva, Monroy Nancy, Silva-Zolezzi Irma, Cobaleda Jesús, Gallego-Aguilera Alicia, Alonso María Elisa, Llerena Adrián

Abstract excerpt

UDP-glucuronosyltransferase 1A4 (UGT1A4) is a phase II drug-metabolizing enzyme that catalyzes the glucuronidation of many clinically-important drugs. Interethnic differences in the genetic polymorphism of UGT1A4 have been reported; however, there is no information in Mexican Mestizos (MMs) and Spaniards (SPs). Furthermore, MM is an admixed population with 26 % of Caucasian genes mainly from Spain. Therefore,...

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PMID: 23277392
DOI: 10.1007/s11033-012-2393-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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