Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring Variation in Known Pharmacogenetic Variants and its Association with Drug Response in Different Mexican Populations.

Pharmaceutical research - 1 Nov 2016

Gonzalez-Covarrubias Vanessa, Martínez-Magaña José Jaime, Coronado-Sosa Regina, Villegas-Torres Beatriz, Genis-Mendoza Alma D, Canales-Herrerias Pablo, Nicolini Humberto, Soberón Xavier

Abstract excerpt

PURPOSE: Information on genetic variants that affect the pharmacokinetics and pharmacodynamics (PK/PD) of drugs in different populations from Mexico is still an ongoing endeavor. Here, we investigate allele frequencies on pharmacogenetic targets in Mexican Mestizos and Natives from three different States and its association with drug efficacy in individuals receiving either anticoagulants or antipsychotic drugs....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acenocoumarol
Share to Anticoagulants

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antipsychotic Agents

Share to Constitutive Androstane Receptor

Share to Genetics, Population

Share to Indians, North American

Share to Mexico

Share to Pharmacogenomic Variants

Source

Identifiers

PMID: 27387170
DOI: 10.1007/s11095-016-1990-5

Genes

ABCB1
DPYD
GSTM1
NAT2
TYMS
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring Variation in Known Pharmacogenetic Variants and its Association with Drug Response in Different Mexican Populations.PMID 27387170Read ↗

Exploring the distribution of genetic markers of pharmacogenomics relevance in Brazilian and Mexican populations.Semantic proximity Read ↗

Clinical genetic variation across Hispanic populations in the Mexican Biobank.Semantic proximity Read ↗

Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicineSemantic proximity Read ↗

Genotype frequencies of VKORC1 and CYP2C9 in native and Mestizo populations from Mexico, potential impact for coumarin dosing.Semantic proximity Read ↗

Rare genetic variants in cellular transporters, metabolic enzymes, and nuclear receptors can be important determinants of interindividual differences in drug response.Semantic proximity Read ↗

Opportunities and Challenges of Population PharmacogenomicsSemantic proximity Read ↗

A Narrative Review on Pharmacogenomics in Psychiatry: Scientific Definitions, Principles, and Practical Resources.Semantic proximity Read ↗

Human loci involved in drug biotransformation: worldwide genetic variation, population structure, and pharmacogenetic implications.Semantic proximity Read ↗

Clinical Pharmacology and Pharmacogenetics in a Genomics Era: The DMET PlatformSemantic proximity Read ↗

Psychiatric Level 1A evidence pharmacogenomics in a Brazilian admixed cohort and global populations.Semantic proximity Read ↗

Population Diversity in Pharmacogenetics: A Latin American Perspective.Semantic proximity Read ↗

Population pharmacogenomics: an update on ethnogeographic differences and opportunities for precision public healthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.