Article
Pharmacogenomic assessment of Mexican and Peruvian populations.
Pharmacogenomics - 1 Jan 2015
Marsh Sharon, King Cristi R, Van Booven Derek J, Revollo Jane Y, Gilman Robert H, McLeod Howard L
Abstract excerpt
BACKGROUND: Clinically relevant polymorphisms often demonstrate population-specific allele frequencies. Central and South America remain largely uncategorized in the context of pharmacogenomics. MATERIALS & METHODS: We assessed 15 polymorphisms from 12 genes (ABCB1 3435C>T, ABCG2 Q141K, CYP1B1*3, CYP2C19*2, CYP3A4*1B, CYP3A5*3C, ERCC1 N118N, ERCC2 K751Q, GSTP1 I105V, TPMT 238G>C, TPMT 460G>A, TPMT 719A>G, TYMS...
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